No. 1 cancer mortality rate. Lung cancer.Diagnose in 40 minutes using genetic scissors

[Anchor]
Korean researchers have developed a technology that can diagnose lung cancer early using genetic scissors.

It is the principle of detecting a trace amount of lung cancer genes released by lung cancer cells into the blood, and it can process samples of 16 patients at once in 40 minutes.

This is reporter Lee Sung Kyu.

[Reporter]
Lung cancer, the number one disease in cancer mortalityIt is important to detect
lung cancer early because the patient has no initial symptoms and the disease worsens without knowing whether it is cancer.In recent years, liquid biopsies using body fluids such as blood and urine have attracted attention, rather than biopsies using


cancer tissue to be removed and examined.

However, the amount of cancer genes in the body fluid was too small, so there was a limit to clinical application.

Korean researchers have developed a technology to diagnose lung cancer early with a very small amount of blood.

The key is genetic scissors technology that accurately recognizes lung cancer genes.

It is a principle that a small amount of lung cancer genes released by cancer cells into the blood are recognized and cut off by gene scissors, and then amplified in large quantities to diagnose them.

The principle is similar to PCR diagnosis, which amplifies and detects genes, but the amplification process is simple and much more efficient.

[Kang Tae-joon / Lead researcher of the Korea Institute of Biotechnology: The current PCR technology uses temperature changes to react to amplify genes by going back and forth. The technology we developed allows gene amplification to proceed quickly at the same temperature without temperature changes..]

The developed diagnostic technology can be detected with 1,000 times fewer samples than PCR diagnosis, and 16 samples can be processed simultaneously in 40 minutes.

The researchers plan to develop and commercialize miniaturization equipment that can be easily carried and diagnosed in cooperation with domestic bio companies.

I'm Lee Sung Kyu of YTN Science.


Video coverage: Kim Young-hwan

Video editing: Hwang Yu-min